Which item cannot be changed on a CII prescription?

On a prescription for a Schedule II (CII) drug, the name of the patient is an immutable element that cannot be altered after the prescription has been issued. The patient’s name is a critical component of the prescription that directly ties the medication to that specific individual. Changing this could lead to significant legal and medical implications, including potential misuse or diversion of controlled substances.

In contrast, while it is generally prohibited to change certain components of a CII prescription, other elements—such as the strength of the drug, quantity, and directions for use—might have some flexibility if amendments are necessary. However, any modifications to these aspects would typically require proper authorization and documentation to maintain compliance with pharmacy regulations. Therefore, the ability to adjust these elements under certain circumstances contrasts with the strict prohibition on altering the patient’s name.