When is generic substitution for brand medications prohibited?

Generic substitution for brand medications is prohibited when the prescriber communicates that preference verbally or in writing. In this context, prescribers have the authority to indicate their preference for a specific brand medication to ensure that the patient receives the treatment they deem most appropriate. This directive can take the form of a written prescription that explicitly states "dispense as written" or through a verbal communication that is noted on the patient's record.

While a pharmacist may have their own professional judgment about medication choices, the prescriber’s instruction has precedence in this scenario. Additionally, patient preference for a brand name medication or insurance mandates for a specific brand do not legally prevent generic substitution unless explicitly instructed by the prescriber. Thus, understanding the prescriber's directive is essential to ensure compliance with state laws and regulations surrounding prescribed medications.