What characteristic of suspensions is evaluated in non-sterile compounding control procedures?

In non-sterile compounding control procedures, evaluating particle size uniformity is essential because it directly affects the stability, efficacy, and safety of the suspension. Proper particle size ensures a uniform distribution of active ingredients, allowing for consistent dosing when the suspension is used. Uniform particle size also influences the suspension’s appearance, viscosity, and the rate at which particles settle over time.

A lack of uniformity in particle size can lead to issues such as settling of larger particles or the formation of cake at the bottom of the container, making it difficult for patients to obtain the correct dosage. Thus, ensuring that the particles are uniformly sized is a crucial aspect of quality control in compounding processes, as it helps maintain the integrity and effectiveness of the prepared suspension.

While color intensity, scent, and the rate of settling are important characteristics to monitor, they are secondary to ensuring that the particle size is consistent, as this is the foundational aspect that influences other physical properties and the overall quality of the suspension.