For non-sterile oral aqueous compounds, what is the designated BUD?

For non-sterile oral aqueous compounds, the designated beyond-use date (BUD) is 14 days. This is based on guidelines established by the United States Pharmacopeia (USP) and is specifically tailored for formulations that are intended to be used within a relatively short time frame due to the stability and potential microbial growth in aqueous solutions.

Aqueous compounds are more susceptible to bacterial contamination and degradation compared to non-aqueous formulations, which is why the 14-day limit is put in place. This time frame allows for adequate safety and efficacy of the compound while minimizing the risk of using a product that may have deteriorated in quality.

In contrast, other options like 30 days, 6 months, or 1 year are typically associated with different types of non-sterile compounds or products that have a much longer shelf-life, such as solid dosage forms or non-aqueous preparations. This distinction is crucial for pharmacy practice, ensuring that compounded medications maintain their therapeutic effectiveness and are safe for patient use.